SAWSAN ABOBAKR ABOHASHEM ZAITONE
• The scientific production by Dr Sawsan Zaitone includes 120 scientific papers published internationally in journals indexed in Scopus and WOS databases
•Collaboration was set with prestigious Arab universities such as King Abdulaziz University and King Saud University, as well as the University of Tabuk and the University of Knowledge in Saudi Arabia
• Dr Sawsan Zaitone supervised 24 masters theses and 4 PhD theses in the field of pharmacology and toxicology at Suez Canal University
• Dr Sawsan participated in the judging and discussion committees for 9 masters theses and 2 PhD theses
• Dr Sawsan is an international reviewer in the number of 189 international journals recognized by WOS and Scopus
• She has participated in a number of local and international conference
• She is working at the Faculty of Pharmacy at Tabuk University and participates in academic teaching, student field training, supervises graduation projects, and participates in multiple research groups to publish scientific research
•Collaboration was set with prestigious Arab universities such as King Abdulaziz University and King Saud University, as well as the University of Tabuk and the University of Knowledge in Saudi Arabia
• Dr Sawsan Zaitone supervised 24 masters theses and 4 PhD theses in the field of pharmacology and toxicology at Suez Canal University
• Dr Sawsan participated in the judging and discussion committees for 9 masters theses and 2 PhD theses
• Dr Sawsan is an international reviewer in the number of 189 international journals recognized by WOS and Scopus
• She has participated in a number of local and international conference
• She is working at the Faculty of Pharmacy at Tabuk University and participates in academic teaching, student field training, supervises graduation projects, and participates in multiple research groups to publish scientific research
Resume
Study Schedule
Research And Literature
Research Projects
Awards
Experience and administrative positions
- Coordinator of Scientific Research at the Faculty of Pharmacy, University of Tabuk and and the secretary of the scientific research unit
- The head of the strategic planning unit at the Faculty of Pharmacy, University of Tabuk since 2022
- Member of the academic affairs unit at the FPUT 2018-June 2024
Qualifications
- Bachelor degree in Pharmaceutical Sciences from Suez Canal University, Egypt
- Masters degree in Pharmaceutical Sciences (neuropharmacology)
- PhD degree in Pharmaceutical Sciences (Behavioral and neuropharmacology)
Research interests
Behavioral and Neuro-pharmacology
Nanoparticle chemotherapy
| Day | Course | Time |
|---|---|---|
| الأحد | Drug dependence and abuse PDPT0403 Lecture | 10:00 - 12:00 |
| الأحد | Drug dependence and abuse PDPT0403 Tutorials | 13:00 - 15:00 |
| الإثنين | Pharmacology 2 Practical | 10:00 - 12:00 |
| الثلاثاء | ACADEMIC ADVISING | 10:00 - 12:00 |
| الثلاثاء | Office hours for Pharmacology 2 | 13:00 - 15:00 |
| الأربعاء | Pharmaceutical field training 2 FT102 (girls) | 08:00 - 16:00 |
| الأربعاء | Academic advising | 13:00 - 15:00 |
| الخميس | Office hours drugs of abuse PDPT0403 | 10:00 - 12:00 |
?-Hederin saponin augments the chemopreventive effect of cisplatin against ehrlich tumors and bioinformatic approach identifying the role of SDF1/CXCR4/p-AKT-1/NF?B signaling
Pharmaceuticals
DOI
10.3390/ph16030405
Advanced Therapeutic Strategy for Managing Surgical Site Infections with Natural Nanoemulsion-Antimicrobial Combination
Frontiers in Pharmacology
DOI
10.3389/fphar.2025.1617184
Antitumor activity and targeting p53-PUMA mRNA expression by 5-flurouracil PLGA-lipid polymeric nanoparticles in mouse mammary carcinomas: comparison to free 5-flurouracil
TOXICOLOGY MECHANISMS AND METHODS
DOI
10.1080/15376516.2023.2294083
Antitumor activity of nitazoxanide against colon cancers: molecular docking and experimental studies based on wnt/?-catenin signaling inhibition
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
DOI
10.3390/ijms22105213
Betanin improves motor function and alleviates experimental Parkinsonism via downregulation of TLR4/MyD88/NF-?B pathway: Molecular docking and biological investigations
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2023.114917
Betanin mitigates vancomycin-induced acute kidney injury in mice and molecular docking indicated inhibition of STAT3 phosphorylation
TISSUE & CELL
DOI
10.1016/j.tice.2025.103159
Betanin protects against diabetic retinal damage via the inhibition of NF-?B/NLRP3/VEGF axis: Insights from network pharmacology and experimental studies
EXPERIMENTAL EYE RESEARCH
DOI
10.1016/j.exer.2026.110863
Beyond Glycemic Control: GLP-1 Receptor Agonists and Their Impact on Calcium Homeostasis in Real-World Patients
Journal of Clinical Medicine
DOI
10.3390/jcm13164896
Celastrol and thymoquinone alleviate aluminum chloride-induced neurotoxicity: Behavioral psychomotor performance, neurotransmitter level, oxidative-inflammatory markers, and BDNF expression in rat brain
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2022.113072
Chemopreventive effect of 5-flurouracil polymeric hybrid PLGA-lecithin nanoparticles against colon dysplasia model in mice and impact on p53 apoptosis
Biomolecules
DOI
10.3390/biom11010109
Chemotherapeutic potential of betanin/capecitabine combination targeting colon cancer: experimental and bioinformatic studies exploring NF?B and cyclin D1 interplay
Frontiers in Pharmacology
DOI
10.3389/fphar.2024.1362739
Design and optimization of omeprazole-curcumin-loaded hydrogel beads coated with chitosan for treating peptic ulcers
Pharmaceuticals
DOI
10.3390/ph16060795
Development of novel pH-sensitive eudragit coated beads containing curcumin-mesalamine combination for colon-specific drug delivery
Gels
DOI
10.3390/gels9040264
Differential effect of three macrolide antibiotics on cardiac pathology and electrophysiology in a myocardial infarction rat model: influence on sodium Nav1. 5 channel expression
Pharmaceuticals
DOI
10.3390/ph14070597
Ethnicity affects the risk factors of acute myocardial infarction and should be considered in educational programs
Frontiers in Cardiovascular Medicine
DOI
10.3389/fcvm.2022.948028
Formulation and characterization of O/W nanoemulsions of hemp seed oil for protection from steatohepatitis: Analysis of hepatic free fatty acids and oxidation markers
Pharmaceuticals
DOI
10.3390/ph15070864
Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury
Frontiers in Chemistry
DOI
10.3389/fchem.2024.1449380
Formulation and characterization of metformin-loaded ethosomes for topical application to experimentally induced skin cancer in mice
Pharmaceuticals
DOI
10.3390/ph15060657
Formulation and evaluation of novel additive-free spray-dried triamcinolone acetonide microspheres for pulmonary delivery: A pharmacokinetic study
Pharmaceutics
DOI
10.3390/pharmaceutics14112354
Hesperetin protects against rotenone-induced motor disability and neurotoxicity via the regulation of SIRT1/NLRP3 signaling
TOXICOLOGY MECHANISMS AND METHODS
DOI
10.1080/15376516.2024.2390646
In Vitro, In Silico, and In Vivo Antineoplastic Activity of Maslinic Acid From Olive Leaves on Diethylnitrosamine?Induced Hepatocellular Carcinoma: Impact on ATP Citrate Lyase …
JOURNAL OF FOOD BIOCHEMISTRY
DOI
10.1155/jfbc/1380085
Influence of surface-modification via PEGylation or chitosanization of lipidic nanocarriers on in vivo pharmacokinetic/pharmacodynamic profiles of apixaban
Pharmaceutics
DOI
10.3390/pharmaceutics15061668
Integrative in silico-in vivo modeling identifies apigenin modulation of TGF-?1/SMAD2 in methotrexate-induced cardiotoxicity
TOXICOLOGY MECHANISMS AND METHODS
DOI
10.1080/15376516.2025.2609605
Irisin improves adiposity and exercise tolerance in a rat model of postmenopausal obesity through enhancing adipo-myocyte thermogenesis
JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
DOI
10.1007/s13105-022-00915-3
Isoliquiritigenin attenuates inflammation and modulates Nrf2/caspase-3 signalling in STZ-induced aortic injury
JOURNAL OF PHARMACY AND PHARMACOLOGY
DOI
10.1093/jpp/rgaa056
Leflunomide induces dose-dependent lung injury in mice via stimulating vimentin and NLRP3 inflammasome production
Frontiers in Pharmacology
DOI
10.3389/fphar.2021.631216
Marula oil nanoemulsion improves motor function in experimental parkinsonism via mitigation of inflammation and oxidative stress
Frontiers in Pharmacology
DOI
10.3389/fphar.2023.1293306
Memantine mitigates ROS/TXNIP/NLRP3 signaling and protects against mouse diabetic retinopathy: Histopathologic, ultrastructural and bioinformatic studies
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2023.114772
Metformin suppresses LRG1 and TGF?1/ALK1-induced angiogenesis and protects against ultrastructural changes in rat diabetic nephropathy
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2022.114128
Molecular Docking, Bioinformatic Analysis, and Experimental Verification for the Effect of Naringin on ADHD: Possible Inhibition of GSK-3? and HSP90
Pharmaceuticals
DOI
10.3390/ph17111436
Molecular docking and experimental validation for the protective effect of betanin against capecitabine-induced myocardial injury: Binding to TLR4 and downregulation of MyD88/NF?B signaling
TISSUE & CELL
DOI
10.1016/j.tice.2026.103475
Nifedipine Improves the Ketogenic Diet Effect on Insulin-Resistance-Induced Cognitive Dysfunction in Rats
Pharmaceuticals
DOI
10.3390/ph17081054
Nifuroxazide mitigates angiogenesis in ehlrich’s solid carcinoma: molecular docking, bioinformatic and experimental studies on inhibition of il-6/jak2/stat3 signaling
MOLECULES
DOI
10.3390/molecules26226858
Nitazoxanide mitigates methotrexate hepatotoxicity in rats: role in inhibiting apoptosis and regulating endoplasmic reticulum stress
Frontiers in Pharmacology
DOI
10.3389/fphar.2024.1491249
Novel mechanism for memantine in attenuating diabetic neuropathic pain in mice via downregulating the spinal HMGB1/TRL4/NF-kB inflammatory axis
Pharmaceuticals
DOI
10.3390/ph14040307
Preoperative Diagnosis Failure for a Rare Gastric Collision Tumor: A Case Report
Diagnostics
DOI
10.3390/diagnostics11040633
Protective effect of topiramate against diabetic retinopathy and computational approach recognizing the role of NLRP3/IL-1?/TNF-? signaling
Biomedicines
DOI
10.3390/biomedicines11123202
Ramipril and ketogenic diet response in cognitive dysfunction of insulin-resistant rats
Frontiers in Pharmacology
DOI
10.3389/fphar.2025.1620139
Recent Advances in the Development of Pro-PROTAC for Selective Protein Degradation
Pharmaceutics
DOI
10.3390/pharmaceutics17091160
Saponin-rich extract of Tribulus terrestris alleviates systemic inflammation and insulin resistance in dietary obese female rats: Impact on adipokine/hormonal disturbances
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2022.112639
Soluble guanylate cyclase agonist, isoliquiritigenin attenuates renal damage and aortic calcification in a rat model of chronic kidney failure
LIFE SCIENCES
DOI
10.1016/j.lfs.2023.121460
Spanlastic nano-vesicles: a novel approach to improve the dissolution, bioavailability, and pharmacokinetic behavior of famotidine
Pharmaceuticals
DOI
10.3390/ph17121614
Tamarindus indica Extract as a Promising Antimicrobial and Antivirulence Therapy
Antibiotics-Basel
DOI
10.3390/antibiotics12030464
The anti-rheumatic drug, leflunomide, induces nephrotoxicity in mice via upregulation of TGF?-mediated p53/Smad2/3 signaling
Toxics
DOI
10.3390/toxics10050274
Topiramate affords neuroprotection in diabetic neuropathy model via downregulating spinal GFAP/inflammatory burden and improving neurofilament production
TOXICOLOGY MECHANISMS AND METHODS
DOI
10.1080/15376516.2023.2196687
Two eco-friendly chromatographic methods evaluated by GAPI for simultaneous determination of the fluoroquinolones moxifloxacin, levofloxacin, and gemifloxacin in their …
Separations
DOI
10.3390/separations9110330
Awareness, attitudes, and self-reported clinical management of antimicrobial-associated neurocognitive adverse effects among healthcare providers in Saudi Arabia
Frontiers in Pharmacology
DOI
10.3389/fphar.2026.1866022
| Project Name | Project Description |
|---|---|
| Protective effect of Caffeic acid phenethyl ester against rotenone induced neurodegeneration: implication for Parkinson’s disease therapy | Funded by the Deanship of Scientific Research in University of Tabuk |
| Modulation of peripheral neuropathy and spinal glia activity in diabetic mice by valproate sodium: possible histone deacetylase inhibition | Funded by the DSR in University of Tabuk (code S-1439-0104) |
| Neuroprotective effect of donepezil against diabetic retinopathy and optic nerve damage: possible downregulation of glutamate receptors and modulation of AMPK/mTOR pathway | Funded by the DSR in University of Tabuk |
| Therapeutic potential of of nanoemulsion preparations of natural oils in alleviating experimental insulin resistance and fatty liver diseases | Funded by the DSR in University of Tabuk (code S-0083-1442) |
- (2020-2021) The award of distinguished staff member in scientific research in Faculty of Pharmacy in University of Tabuk at academic year 1442 H
- Award of best applied research from the community service section (Prof Ahmed Askar Award) the most prestigious award in Suez Canal University in 2021
- Award of best applied research from the higher studies and research section in Suez Canal University in 2021
- The best moderated e-poster in the 3rd annual Cardiology Conference of Suez Canal Authority, held at Fairmont-Heliopolis Hotel, Cairo, Egypt [28th April 2016]
- The best moderated e-poster in the 2nd annual Cardiology Conference of Suez Canal Authority in collaboration with the Egyptian Society of Cardiology, held at Intercontinental City Stars, Cairo, Egypt [23-24 April 2015]
- One of the top 2% scientists in the world as announced by Stanford University in October 2021
- Position number 4 in scientists working in Saudi Universities who peer reviews for WOS journals in 2021
- Winner of the second place in the best poster presentation in SIPHA conference 2022 held in Riyadh, Saudi Arabia
- Winner of the most cited article award (duration 2019-2021) in University of Tabuk
- The Polymers 2021 Outstanding Reviewer Award
- The third place prize in best poster competition (regarding the topic) in DUPHAT conference 2025 held on 10-12 January 2024
- The third place prize in best poster competition (regarding the topic) in DUPHAT conference 2025 held on 10-12 January 2024
College
Faculty of Pharmacy
General specialization
Pharmaceutical Toxicology
Exact Specialty
Mechanistic Toxicology
Academic degree (rank)
Doctorate
Nationality
Egyptian
Job Title
Professor