REEM SHELWEEH H ALSHAMAN
د ريم الشامان حاصلة على درجة الدكتوراة في العلوم الصيدلية ( علم الأدوية) عام 2016 من جامعة تكساس- امريكا, استاذ مساعد في قسم علم الأدوية والسموم تشغل حالياً منصب وكيلة كلية الصيدلة لشطر الطالبات -وكيلة كلية الصيدلة للدراسات العليا والبحث العلمي بالإضافة الى اشرافها على قسم علم الأدوية والسموم شطر الطالبات
Resume
Study Schedule
Research And Literature
Research Projects
Awards
Experience and administrative positions
- وكيلة كلية الصيدلة شطر الطالبات
- وكيلة كلية الصيدلة للدراسات العليا والبحث العلمي
- مشرفة قسم علم الأدوية والسموم
Qualifications
- بكالوريوس العلوم الصيدلية
- ماجستير العلوم الصيدلية (علم الأدوية)
- دكتوراه العلوم الصيدلية (علم الأدوية)
Research interests
Molecular Pharmacology
| Day | Course | Time |
|---|---|---|
| الإثنين | Office hours | 10:00 - 12:00 |
| الأربعاء | Pharmacology-2 ( PDPT0322) | 08:00 - 10:00 |
| الأربعاء | office hour | 12:00 - 13:00 |
?-Hederin saponin augments the chemopreventive effect of cisplatin against ehrlich tumors and bioinformatic approach identifying the role of SDF1/CXCR4/p-AKT-1/NF?B signaling
Pharmaceuticals
DOI
10.3390/ph16030405
Acetyl-L-carnitine protects against LPS induced depression via PPAR-? induced inhibition of NF-?B/NLRP3 pathway
Archives of Medical Science
DOI
10.5114/aoms/145157
Betanin mitigates vancomycin-induced acute kidney injury in mice and molecular docking indicated inhibition of STAT3 phosphorylation
TISSUE & CELL
DOI
10.1016/j.tice.2025.103159
Carvacrol alleviates hyperuricemia-induced oxidative stress and inflammation by modulating the NLRP3/NF-?B pathwayt
Drug Design Development and Therapy
DOI
10.2147/dddt.s343978
Carveol Attenuates Seizure Severity and Neuroinflammation in Pentylenetetrazole?Kindled Epileptic Rats by Regulating the Nrf2 Signaling Pathway
Oxidative Medicine and Cellular Longevity
DOI
10.1155/2021/9966663
Carveol a naturally-derived potent and emerging Nrf2 activator protects against acetaminophen-induced hepatotoxicity
Frontiers in Pharmacology
DOI
10.3389/fphar.2020.621538
Chrysophanol Attenuates Cognitive Impairment, Neuroinflammation, and Oxidative Stress by TLR4/NF?B-Nrf2/HO-1 Signaling in Ethanol-Induced Neurodegeneration
NEUROCHEMICAL RESEARCH
DOI
10.1007/s11064-025-04486-9
Comprehensive study of atorvastatin nanostructured lipid carriers through multivariate conceptualization and optimization
Pharmaceutics
DOI
10.3390/pharmaceutics13020178
Computational and experimental approaches exploring the role of hesperetin in improving autophagy in rat diabetic retinopathy
Biomedicines
DOI
10.3390/biomedicines12030552
Development of novel pH-sensitive eudragit coated beads containing curcumin-mesalamine combination for colon-specific drug delivery
Gels
DOI
10.3390/gels9040264
Enhanced cardioprotective activity of ferulic acid-loaded solid lipid nanoparticle in an animal model of myocardial injury
TOXICOLOGY AND APPLIED PHARMACOLOGY
DOI
10.1016/j.taap.2023.116657
Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma in rats
REDOX REPORT
DOI
10.1080/13510002.2024.2365590
Evaluating the Safety and Efficacy of PD-1 Inhibitors in HIV Patients Diagnosed with Lung Cancer: A Systematic Review
Pharmaceuticals
DOI
10.3390/ph18111654
Fluorometric detection of quinolones via AIE and FRET with terbium-doped carbon dots and copper nanoclusters
Food Chemistry
DOI
10.1016/j.foodchem.2024.142076
Formulation and characterization of O/W nanoemulsions of hemp seed oil for protection from steatohepatitis: Analysis of hepatic free fatty acids and oxidation markers
Pharmaceuticals
DOI
10.3390/ph15070864
Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury
Frontiers in Chemistry
DOI
10.3389/fchem.2024.1449380
Formulation and characterization of doxycycline-loaded polymeric nanoparticles for testing antitumor/antiangiogenic action in experimental colon cancer in mice
Nanomaterials
DOI
10.3390/nano12050857
Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and the inflammatory cascade by modulating the PI3K/Akt and JNK/NF-?B pathways
Archives of Medical Science
DOI
10.5114/aoms/146792
Influence of surface-modification via PEGylation or chitosanization of lipidic nanocarriers on in vivo pharmacokinetic/pharmacodynamic profiles of apixaban
Pharmaceutics
DOI
10.3390/pharmaceutics15061668
Leflunomide-induced cardiac injury in adult male mice and bioinformatic approach identifying Nrf2/NF-?b signaling interplay
TOXICOLOGY MECHANISMS AND METHODS
DOI
10.1080/15376516.2024.2322666
Marula oil nanoemulsion improves motor function in experimental parkinsonism via mitigation of inflammation and oxidative stress
Frontiers in Pharmacology
DOI
10.3389/fphar.2023.1293306
QNZ alleviated hepatocellular carcinoma by targeting inflammatory pathways in a rat model
CYTOKINE
DOI
10.1016/j.cyto.2021.155710
Quercetin alleviated inflammasome-mediated pyroptosis and modulated the mTOR/P70S6/P6/eIF4E/4EBP1 pathway in ischemic stroke
Pharmaceuticals
DOI
10.3390/ph16081182
Recent Advances in the Development of Pro-PROTAC for Selective Protein Degradation
Pharmaceutics
DOI
10.3390/pharmaceutics17091160
Sensing the invisible: Ultrasensitive and selective colorimetric detection of E. coli O157: H7 based on masking the peroxidase-mimetic activity of aptamer-modified Au/Fe3O4
Food Chemistry
DOI
10.1016/j.foodchem.2024.138564
Spanlastic nano-vesicles: a novel approach to improve the dissolution, bioavailability, and pharmacokinetic behavior of famotidine
Pharmaceuticals
DOI
10.3390/ph17121614
The Improvement of Experimentally Induced Gastric Ulcers in Rats by Inhibiting Vascularization Through the Blocking of the TNF?? Type 1 Receptor
Immunity Inflammation and Disease
DOI
10.1002/iid3.70279
The Interplay of Carveol and All-Trans Retinoic Acid (ATRA) in Experimental Parkinson’s Disease: Role of Inflammasome-Mediated Pyroptosis and Nrf2
NEUROCHEMICAL RESEARCH
DOI
10.1007/s11064-024-04226-5
The Link between occurrence of class I integron and acquired aminoglycoside resistance in clinical MRSA isolates
Antibiotics-Basel
DOI
10.3390/antibiotics10050488
The anti-rheumatic drug, leflunomide, induces nephrotoxicity in mice via upregulation of TGF?-mediated p53/Smad2/3 signaling
Toxics
DOI
10.3390/toxics10050274
The protective role of Astaxanthin against the central and peripheral detrimental effects for chronic administration of sweeteners in a rat model: Involvement of multiple signaling axes
JOURNAL OF NUTRITIONAL BIOCHEMISTRY
DOI
10.1016/j.jnutbio.2026.110309
The supportive role of NSC328382, a P2X7R antagonist, in enhancing the inhibitory effect of CRID3 on NLRP3 inflammasome activation in rats with dextran sodium sulfate-induced …
Journal of Inflammation Research
DOI
10.2147/jir.s315938
Therapeutic Impact of Zanubrutinib in Chronic Lymphocytic Leukemia: Evidence from a Systematic Review and Single-Arm Meta-Analysis
Pharmaceuticals
DOI
10.3390/ph18111674
Therapeutic effects of blocking ?-catenin against hepatocellular carcinoma-induced activation of inflammation, fibrosis and tumor invasion
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2021.111216
Therapeutic effects of sulforaphane in ulcerative colitis: effect on antioxidant activity, mitochondrial biogenesis and DNA polymerization
REDOX REPORT
DOI
10.1080/13510002.2022.2092378
Two new HPLC methods, assessed by GAPI, for simultaneous determination of four antipsychotics in pharmaceutical formulations: A comparative study
Separations
DOI
10.3390/separations9080220
Ultrasensitive detection of zineb using a CoMn-MOF/rGO molecularly imprinted electrochemical sensor
MICROCHIMICA ACTA
DOI
10.1007/s00604-025-07326-3
| Project Name | Project Description |
|---|---|
| Antitumor activity of polymeric nanoparticles of doxycycline versus free doxycycline in experimental colon cancer: effect on tumor angiogenesis | في المملكة العربية السعودية ، يعد سرطان القولون والمستقيم هو أوسع سرطان في الانتشار فى الذكور (559 ٪) والثالث في الإناث (441 ٪) تمثل منطقة تبوك المنطقة الخامسة الأكثر شيوعًا في المملكة العربية السعودية المتأثرة بسرطان القولون والمستقيم وفقًا لأحدث تحديثات سجل السرطان السعودي في يونيو 2016 تهدف هذه الدراسة إلى تحديد فائدة الأدوية المضادة للسرطان المحضرة في شكل جزيئات النانومترية في علاج سرطان القولون التجريبي المستحدث في الفئران ومقارنة فعالية هذه الأدوية النانومترية الحجم مع الأشكال الحرة سيتم تقسيم الفئران إلى مجموعات فرعية تعالج بواسطة جرعات مختلفة من دواء Doxycycline في شكل حر وفي شكل نانومتري مصمم بواسطة تقنية البوليمر وسيتم تقدير فعالية الأدوية عن طريق حجم الورم الصلب و شواهد التشريح المرضي لمقارنة شدة تقدم السرطان سيتم استخدام صبغات الكيمياء المناعية لمعرفة تمركز الخلايا الالتهابية والخلايا المبطنة للأوعية الدموية بالإضافة إلى ذلك ، سيتم استخدام تحليل Western blot لقياس مستويات بروتينات angiogenesis من المتوقع أن يكون للتشكيلات النانومترية لأدوية العلاج الكيميائي خصائص حركية دوائية أفضل وتوافر حيوي أفضل النتائج الإيجابية قد تدعم وجهة نظر لتضمن تكنولوجيا النانو في مجال علم الأورام |
- The Annual Meeting of Saudi pharmaceutical society: 2nd place student poster (Pharmaceutical Sciences): The anti-rheumatic drug, Leflunomide, produces nephrotoxic effect through upregulation of TGFβ-stimulated p53/Smad2/3 pathway
College
Faculty of Pharmacy
General specialization
Pharmacology
Exact Specialty
Cardiovascular pharmacology
Academic degree (rank)
Doctorate
Nationality
SAUDI
Job Title
Assoc. Prof.