NEHAL MOHSEN AHMED ELSHERBINY
Nehal Elsherbiny
• Associate professor of Biochemistry
• Scopus profile https://wwwscopuscom/authid/detailuri?authorId=55441041500
• Publon profile https://publonscom/researcher/3254210/nehal-elsherbiny/
• More than 100 Publications
• Reviewer for more than 100 Scopus/ISI journals
• Associate editor for Frontiers in Endocrinology Journal
• Special issue lead guest editor for the Journal of Diabetes Research and Frontiers in Endocrinology Journal
• Listed in Top 2% of Scientists Worldwide identified by Stanford University
• Associate professor of Biochemistry
• Scopus profile https://wwwscopuscom/authid/detailuri?authorId=55441041500
• Publon profile https://publonscom/researcher/3254210/nehal-elsherbiny/
• More than 100 Publications
• Reviewer for more than 100 Scopus/ISI journals
• Associate editor for Frontiers in Endocrinology Journal
• Special issue lead guest editor for the Journal of Diabetes Research and Frontiers in Endocrinology Journal
• Listed in Top 2% of Scientists Worldwide identified by Stanford University
Resume
Study Schedule
Research And Literature
Research Projects
Awards
Experience and administrative positions
- General co-ordinator of the academic affairs unit-female section
- Member of student activities unit
- Member of academic advising committee
- Supervisor of Pharmaceutical Chemistry department (female section)
- Member of creativity and talent unit
- Member of Institutinal Research Ethical Review-University of Tabuk
- Supervisor of Community service unit-Faculty of Pharmacy
- Member of quality and academic accreditation unit
Qualifications
- • 05/2013: PhD in Pharmaceutical Sciences (Biochemistry)-Faculty of Pharmacy, Mansoura University, Egypt (Joint supervision with Georgia Regents University- Georgia- United States of America) Title of PhD dissertation “The effect of adenosine receptors and adenosine metabolizing enzymes in rodents with diabetic complications
- • 05/2010: Master Degree in Pharmaceutical Science (Biochemistry), Faculty of Pharmacy, Mansoura University, Egypt Title of master dissertation: “Biochemical study of some glycoproteins and their degradation enzymes in patients with hepatocellular carcinoma
- • 07/2007: Bachelor of Pharmacy, Degree excellent with honor, top student throughout the 5 year-period of study, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
Research interests
Targeting underlying molecular pathogenic mechanisms of common diseases in Tabuk area such as cancer and diabetes mellitus
Assessment of potential therapeutic and protective effects of recent strategies such as stem cells, exosomes and nano-formulated drugs for treatment of common disease in Tabuk area
(Investigation of existing drugs for new therapeutic purpose (drug repurposing
| Day | Course | Time |
|---|---|---|
| الأحد | --- | 15:00 - 17:00 |
?-Lipoic Acid Protects against Cyclosporine A-Induced Hepatic Toxicity in Rats: Effect on Oxidative Stress, Inflammation, and Apoptosis
Toxics
DOI
10.3390/toxics10080442
Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway
Stem Cell Research & Therapy
DOI
10.1186/s13287-021-02454-y
Anti-inflammatory/anti-apoptotic impact of betulin attenuates experimentally induced ulcerative colitis: An insight into tlr4/nf-kb/caspase signalling modulation
Environmental Toxicology and Pharmacology
DOI
10.1016/j.etap.2021.103750
Astrocytes profiling in acute hepatic encephalopathy: Possible enrolling of glial fibrillary acidic protein, tumor necrosis factor-alpha, inwardly rectifying potassium channel …
Frontiers in Cellular Neuroscience
DOI
10.3389/fncel.2022.896172
Atorvastatin Ameliorates Cerebral Cortical Pathological and Cognitive Alterations in Aged Rats: Histological & Immunohistochemical Study
TISSUE & CELL
DOI
10.1016/j.tice.2025.103184
CRISPR/Cas9 System as a Promising Therapy in Thalassemia and Sickle Cell Disease: A Systematic Review of Clinical Trials
MOLECULAR BIOTECHNOLOGY
DOI
10.1007/s12033-025-01368-x
Canagliflozin Reduce la Respuesta Contr?ctil del Coraz?n Aislado de Ratas Adultas Normales
INTERNATIONAL JOURNAL OF MORPHOLOGY
DOI
10.4067/s0717-95022022000501300
Chitosan-coated nanoemulsion for the direct nose-to-brain delivery of sildenafil: development and in vivo evaluation in a brain oxidative stress and inflammation model
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI
10.1016/j.jddst.2024.105842
Curcumin Modulates Oxidative Stress, Fibrosis, and Apoptosis in Drug-Resistant Cancer Cell Lines
Life-Basel
DOI
10.3390/life12091427
Curcumin-loaded gold nanoparticles with enhanced antibacterial efficacy and wound healing properties in diabetic rats
INTERNATIONAL JOURNAL OF PHARMACEUTICS
DOI
10.1016/j.ijpharm.2024.124761
Dapagliflozin, Liraglutide, and Their Combination Attenuate Diabetes Mellitus-Associated Hepato-Renal Injury—Insight into Oxidative Injury/Inflammation/Apoptosis Modulation
Life-Basel
DOI
10.3390/life12050764
Decoding Diabetes Biomarkers and Related Molecular Mechanisms by Using Machine Learning, Text Mining, and Gene Expression Analysis
International Journal of Environmental Research and Public Health
DOI
10.3390/ijerph192113890
Design, synthesis and pharmacological screening of novel renoprotective methionine-based peptidomimetics: amelioration of cisplatin-induced nephrotoxicity
BIOORGANIC CHEMISTRY
DOI
10.1016/j.bioorg.2021.105100
Development and evaluation of fusidic acid myrrh oil organogel for the reversal of Gram-negative bacterial resistance and improvement of wound-healing potential
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI
10.1016/j.jddst.2025.107247
Development and optimization of flaxseed oil nanoemulsions: implications for ulcerative colitis treatment
JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY
DOI
10.1080/01932691.2025.2456530
Development, optimization, and assessment of losartan nano-bilosomes to mitigate diabetes-induced microvascular complications in Sprague Dawley rats
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI
10.1016/j.jddst.2023.105295
Diacerein ameliorates testosterone-induced benign prostatic hyperplasia in rats: Effect on oxidative stress, inflammation and apoptosis
International Immunopharmacology
DOI
10.1016/j.intimp.2021.108082
Diacerein attenuates 1, 2?dimethylhydrazine induced colon cancer progression in rats: Modulation of IL?6/STAT3/lncRNA HOTAIR pathway
FASEB JOURNAL
DOI
10.1096/fasebj.2022.36.s1.r3035
Diacerein's Antiproliferative Effects Alone and with 5-Fluorouracil in an Ehrlich Solid Tumour Model: Molecular Docking, Molecular Dynamics Simulation Studies, and Experimental …
European Journal of Pharmacology
DOI
10.1016/j.ejphar.2025.177564
Effect of Diacerein on HOTAIR/IL-6/STAT3, Wnt/?-Catenin and TLR-4/NF-?B/TNF-? axes in colon carcinogenesis
Environmental Toxicology and Pharmacology
DOI
10.1016/j.etap.2022.103943
Effect of bone marrow mesenchymal stem cells-derived exosomes on diabetes-induced retinal injury: Implication of Wnt/b-catenin signaling pathway
BIOMEDICINE & PHARMACOTHERAPY
DOI
10.1016/j.biopha.2022.113554
Enhanced skin permeation and controlled release of ?-sitosterol using cubosomes encrusted with dissolving microneedles for the management of alopecia
Pharmaceuticals
DOI
10.3390/ph16040563
Exercise augments the effect of SGLT2 inhibitor dapagliflozin on experimentally induced diabetic cardiomyopathy, possible underlying mechanisms
Metabolites
DOI
10.3390/metabo12070635
Exosomes in COVID?19 infection: Focus on role in diagnosis, pathogenesis, immunity, and clinical trials
CELL BIOLOGY INTERNATIONAL
DOI
10.1002/cbin.12014
Exosomes: Isolation, characterization, and biomedical applications
CELL BIOLOGY INTERNATIONAL
DOI
10.1002/cbin.11620
Exploring the role of Müller cells-derived exosomes in diabetic retinopathy
MICROVASCULAR RESEARCH
DOI
10.1016/j.mvr.2024.104695
Formulation and characterization of cholesterol-based nanoparticles of gabapentin protecting from retinal injury
Frontiers in Chemistry
DOI
10.3389/fchem.2024.1449380
Functional recellularization of acellular rat liver scaffold by induced pluripotent stem cells: Molecular evidence for wnt/b-catenin upregulation
Cells
DOI
10.3390/cells10112819
Ginger oil nanoemulsion formulation augments its antiproliferative effect in ehrlich solid tumor model
Foods
DOI
10.3390/foods12224139
Insights in renal endocrinology: 2021
Frontiers in Endocrinology
DOI
10.3389/fendo.2022.1003683
Isoliquiritigenin attenuates inflammation and modulates Nrf2/caspase-3 signalling in STZ-induced aortic injury
JOURNAL OF PHARMACY AND PHARMACOLOGY
DOI
10.1093/jpp/rgaa056
Lyophilized MSC-EVs attenuates COVID-19 pathogenesis by regulating the JAK/STAT pathway
Stem Cell Research & Therapy
DOI
10.1186/s13287-025-04284-8
MSCs–derived EVs protect against chemotherapy-induced ovarian toxicity: role of PI3K/AKT/mTOR axis
Journal of Ovarian Research
DOI
10.1186/s13048-024-01545-7
Maxillary mucormycosis osteomyelitis in post COVID-19 patients: a series of fourteen cases
Diagnostics
DOI
10.3390/diagnostics11112050
Microneedle mediated transdermal delivery of ?-sitosterol loaded nanostructured lipid nanoparticles for androgenic alopecia
DRUG DELIVERY
DOI
10.1080/10717544.2022.2120927
Multilineage Differentiating Stress Enduring (Muse) Cells: A New Era of Stem Cell-Based Therapy
Cells
DOI
10.3390/cells12131676
Nanogold Particles Suppresses 5-Flurouracil-Induced Renal Injury: An Insight into the Modulation of Nrf-2 and Its Downstream Targets, HO-1 and ?-GCS
MOLECULES
DOI
10.3390/molecules26247684
Neuroprotective effect of morin hydrate against attention-deficit/hyperactivity disorder (ADHD) induced by MSG and/or protein malnutrition in rat pups: Effect on oxidative …
Pharmaceuticals
DOI
10.3390/ph15081012
Nifuroxazide repurposing for protection from diabetes?induced retinal injury in rats: Implication of oxidative stress and JAK/STAT3 axis
BIOFACTORS
DOI
10.1002/biof.2011
Optimization and In Vitro Characterization of Telmisartan Loaded Sodium Alginate Beads and Its In Vivo Efficacy Investigation in Hypertensive Induced Animal Model
Pharmaceutics
DOI
10.3390/pharmaceutics15020709
Optimized Nanostructured Lipid Carriers for Metformin: Enhanced Anti-Inflammatory Activity and Protection Against Type 2 Diabetes-Induced Organ Damage
International Journal of Nanomedicine
DOI
10.2147/ijn.s506631
Origanum majorana L. Extract Attenuated Benign Prostatic Hyperplasia in Rat Model: Effect on Oxidative Stress, Apoptosis, and Proliferation
Antioxidants
DOI
10.3390/antiox11061149
P-glycoproteins in the Pathology and Treatment of Alzheimer's Disease
Letters in Drug Design & Discovery
DOI
10.2174/0115701808293022240216070603
Polycaprolactone nanocapsule-loaded carbopol hydrogel enhances fusidic acid efficacy against Gram-negative bacteria and promotes wound healing
INTERNATIONAL JOURNAL OF PHARMACEUTICS
DOI
10.1016/j.ijpharm.2025.125735
Possible cytotoxic effect of allantoin on oral squamous cell carcinoma stemness (in vivo and in vitro model
FASEB JOURNAL
DOI
10.1096/fasebj.2022.36.s1.r3123
Pramipexole protects against diabetic neuropathy: Effect on oxidative stress, TLR4/IRAK-1/TRAF-6/NF-?B and downstream inflammatory mediators
International Immunopharmacology
DOI
10.1016/j.intimp.2024.111514
Preparation and characterization of novel polyelectrolyte liposomes using chitosan succinate layered over Chitosomes: a potential strategy for colon cancer treatment
Biomedicines
DOI
10.3390/biomedicines12010126
Prophylactic evidence of MSCs-derived exosomes in doxorubicin/trastuzumab-induced cardiotoxicity: beyond mechanistic target of NRG-1/Erb signaling pathway
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
DOI
10.3390/ijms23115967
Punicalagin’s protective effects on Parkinson’s progression in socially isolated and socialized rats: insights into multifaceted pathway
Pharmaceutics
DOI
10.3390/pharmaceutics15102420
Revised title: Design, synthesis, and biological evaluation of Benzimidazole–Aminopyrimidine hybrids as selective P38? MAPK inhibitors targeting Neuroinflammation in an AlCl3-induced rat model of Alzheimer's disease
BIOORGANIC CHEMISTRY
DOI
10.1016/j.bioorg.2025.109391
Role of dapagliflozin and liraglutide on diabetes-induced cardiomyopathy in rats: implication of oxidative stress, inflammation, and apoptosis
Frontiers in Endocrinology
DOI
10.3389/fendo.2022.862394
The Combined Anti-Tumor Efficacy of Bioactive Hydroxyapatite Nanoparticles Loaded with Altretamine
Pharmaceutics
DOI
10.3390/pharmaceutics15010302
The Implication of Mechanistic Approaches and the Role of the Microbiome in Polycystic Ovary Syndrome (PCOS): A Review
Metabolites
DOI
10.3390/metabo13010129
The Possible Mechanisms of Cu and Zn in the Treatment and Prevention of HIV and COVID-19 Viral Infection
BIOLOGICAL TRACE ELEMENT RESEARCH
DOI
10.1007/s12011-023-03788-9
Vitamin K2 (MK-7) intercepts Keap-1/Nrf-2/HO-1 pathway and hinders inflammatory/apoptotic signaling and liver aging in naturally aging rat
Antioxidants
DOI
10.3390/antiox11112150
Vitamin K2 (MK?7) modulated Nrf2/NLRP3/caspase?1 axis to protect against age?related structural and cognitive deterioration in naturally aged rats
FASEB JOURNAL
DOI
10.1096/fasebj.2022.36.s1.r3319
Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats
Antioxidants
DOI
10.3390/antiox11030514
Optimization and evaluation of Olmesartan medoxomil spanlastics for the management of epilepsy
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
DOI
10.1016/j.jddst.2026.108487
| Project Name | Project Description |
|---|---|
| Possible cytotoxic effect of allantoin on oral squamous cell carcinoma stemness (in vivo and in vitro model) | Funded by Research unit, AlMaarefa University, Riyadh, Saudi Arabia |
| Targeting IL-6/STAT3/ lncRNA HOTAIR axis for treatment of colorectal cancer | Funded by Research unit, AlMaarefa University, Riyadh, Saudi Arabia |
| Novel Strategy for Alleviating Diabetic Complications: Targeting Sirt-1 for renal, retinal and arterial injury | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Development of new strategies for treatment of breast cancer: Implication of Notch signaling | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Neuroprotective effect of donepezil against diabetic retinopathy and optic nerve damage: possible downregulation of glutamate receptors and modulation of AMPK/mTOR pathway | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Effect of Calycocin on Diabetic Nephropathy: Implication of IL-33/ST2 Signaling Pathway | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Role of Valproate sodium in alloxan diabetic mice: influence on spinal histone deacetylase inhibition and glia reactivity | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Study of the reno-protective effect of nifuroxazide in diabetic nephropathy | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Protective effect of Caffeic acid phenethyl ester against rotenone-induced neurodegeneration: implication for Parkinson’s disease therapy | Funded by Deanship of Scientific Research, University of Tabuk, Tabuk, Saudi Arabia |
| Control of heparin Sulfate Proteoglycans degradation: New therapy for Hepatocellular Carcinoma | Funded by Mansoura University, Mansoura, Egypt |
| Design and development of polymer coated microneedle-mediated delivery of β-sitosterol for the treatment of androgenic alopecia | Funded by Ministry of High Education, Saudi Arabia |
| Sleep Deprivation-Induced Brain Deficits in Naturally Aged Rats and Role of Oxytocin: Behavioral, Cognitive, And Molecular Evidence | Hevolution Foundation, Riyadh, Saudi Arabia, 2023 |
| Unlocking the Link: Nutritional Deficiency and Blood Barrier Dysfunction in Aging Eye and Brain, Unveiling the Role of TRP Channels, Ca+2 Influx, and Stress Pathways | Hevolution Foundation, Riyadh, Saudi Arabia, 2025 |
- Mansoura University Honor of Academic achievement in Pharmaceutical School (2002-2007)
- Egyptian Government Scholarship Award to obtain PhD degree in collaboration with Medical College of Georgia, USA (Joint Supervision)
- Egyptian Government Scholarship Award for postdoctoral training in Georgia Regents University, USA (post doc training)
- Excellence award (Best staff member)-University of Tabuk, Tabuk, Saudi Arabia, 2019
- 1st position for best research poster entitled “Calycosin suppressed inflammation in diabetes induced renal injury: potential role of IL-33 signaling pathway The 9th Scientific Conference of the Department of Pharmaceutical Care, Tabuk health, under the title “immune mediated inflammatory diseases , 10-11th April 2019, Tabuk, Saudi Arabia
- 7th position for best student poster entitled “Umbilical Cord Stem Cells: Background, Processing and Applications Dubai Pharmaceutical & Technologies Exhibition, 25th-27th Feb 2020, Dubai, UAE
- State Encouragement Award in Medical Sciences, 2020 provided by Ministry of High Education and Sceintific Research, Egypt (the award is given to the top 7 scientists (Medical Sciences) in the Egyptian universities under age 40 based on their scientific activity)
- 1st place award for best student research poster in pharmaceutical sciences, Saudi International Pharmaceutical Conference & Workshop (SIPHA), 3th-5th Jan 2023, Dammam, Saudi Arabia
- 2nd place award - best display student poster- DUPHAT-2025
- 2nd place award - innovative student poster- DUPHAT-2025
College
Faculty of Pharmacy
General specialization
Pharmaceutical Chemistry
Exact Specialty
Biochemistry
Academic degree (rank)
Doctorate
Nationality
Egyptian
Job Title
Assoc. Prof.