رمضان محمود محمد علي
Doctor of Philosophy Department of Pharmacology and Pharmacoepidemeology Analytical chemistry lab, Faculty of Medicine Heidelberg University, Heidelberg, Germany 2013
MSc in Pharmaceutical Science Faculty of Pharmacy, Assiut Univ, Assiut, Egypt 2006
University of Al-Azhar, Assuit, Egypt 1998 Bachelor of Pharmacy (Very Good)
الخبرات والمناصب الإدارية
- Head of Analytical Chemistry Department Faculty of Pharmacy Al-Azhar University Assuit Branch
المؤهلات العلمية
- Doctor of Philosophy Department of Pharmacology and Pharmacoepidemeology
الاهتمامات البحثية
Analytical and Bioanalytical techniques for quantification of different material in different matrices design and construct the specific electro-sensor for determination of specific material in food and enviromental samples
| اليوم | المادة | الوقت |
|---|---|---|
| الأحد | Medicinal Chemistry-1 PDPC0342 (P) 1045 | 13:00 - 15:00 |
| الثلاثاء | Medicinal Chemistry-1 PDPC0342 (P) 1044 | 13:00 - 15:00 |
| الأربعاء | تدريب صيدلي ميداني -2 | 10:00 - 14:00 |
- 1 Mohamed M El-Wekil, Hamada Mohamed Halby, Mahmoud Darweesh, Mohamed E Ali & Ramadan Ali An innovative dual recognition aptasensor for specific detection of Staphylococcus aureus based on Au/Fe3O4 binary hybrid Scientific Reports 12, 12502 (2022)
- 2 Ahmed A Hamad Ramadan Ali, and Sayed M Derayea A simple single jar “on–off fluorescence designed system for the determination of mitoxantrone using an eosin Y dye in raw powder, vial, and human biofluids RSC Advances, 12 (2022)
- 3 Ashraf M Mahmoud, Mohamed M El-Wekil, Ramadan Ali, Hany A Batakoushy & Reem Y Shahin Double-signal quantification of amoxicillin based on interaction with 4-aminoantipyrine at copper and nitrogen co-doped carbon quantum dots as an artificial nanozyme, Microchemica Acta, 189 (2022)
- 4 Ashraf M Mahmoud, Mater HMahnashi, Adel Al Fatease, Mahmoud AHMostafa Mohamed, MEl-Wekil, Ramadan Ali Fluorometric and electrochemical dual-mode detection of toxic flavonoid rutin based on new nitrogen and sulfur co-doped carbon dots: Enhanced selectivity based on masking the interfering flavonoids with BSA complexation, J of food composition and analysis, 108, 104428 (2022)
- 5 Mohamed A Abdel-Lateef, Mahmoud A Omar, Ramadan Ali, Albandary Almahri, Sayed M Derayea Innovative Thin-Layer Chromatography/Fluorescence Detection Approach for Sensitive and Specific Determination of Ledipasvir in Rats’ Feces and Pharmaceutical Dosage Form Journal of Chromatographic Science 2021
- 6 Ahmed AAbu-hassan, Ramadan Ali, Sayed MDerayea A new convenient methodology based on dihydropyridine derivative for selective fluorimetric analysis of baclofen: Application to spiked urine and content uniformity evaluation Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 248 (2021), 119165
- 7 Ahmed A Hamad Ramadan Ali, and Sayed M Derayea Investigating the interaction of mitoxantrone with anionic surfactants by spectrofluorimetry and its application for the feasible analysis of pharmaceutical preparation and biological fluids Luminescence, 36 (2021), 443–453
- 8 Ahmed AAbu-hassan, Ramadan Ali, Sayed MDerayea A new feasible approach based on utility of ninhydrin for selective fluorimetric analysis of baclofen Application to content uniformity evaluation Luminescence (2020), 1-7
- 9 Ahmed AAbu-hassan, Ramadan Ali, Sayed MDerayea A new approach based on isoindole formation reaction for sensitive fluorimetric assay of milnacipran in tablets and biological fluids (plasma/urine) RSC Adv, 10, (2020) 38884-38889
- 10 Sayed M Derayea Ramadan Ali, and Ahmed A Hamad Facile one-pot green solvent synergized fluorescence reaction for determination of doxorubicin in presence of paclitaxel co-administered drug, Application to stability study and analysis in bulk, vial and biological fluids Arabian Journal of Chemistry 13, (2020), 8026-8038
- 11 Mohamed MEl-Wekil Mahmoud Darweesh, Montaser Sh A Shaykoond and Ramadan Ali Enzyme-free and label-free strategy for electrochemical oxaliplatin aptasensing by using rGO/MWCNTs loaded with AuPd nanoparticles as signal probes and electro-catalytic enhancers Talanta , 217, (2020), 121084
- 12 Ahmed AAbu-hassan, Ramadan Ali, Sayed MDerayea One-pot micellar augmented native fluorescence for facile fluorimetric assay of dapoxetine hydrochloride in biological plasma and tablets a Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 239 (2020) 118512
- Ahmed AAbu-hassan, Ramadan Ali, Sayed MDerayea One-pot micellar augmented native fluorescence for facile fluorimetric assay of dapoxetine hydrochloride in biological plasma and tablets Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 239 (2020) 118474
- 14 Mohamed Abdel-Lateef, Ramadan Ali, Mahmoud Omar, Sayed Derayea Micellar‐based spectrofluorimetric method for the selective determination of ledipasvir in the presence of sofosbuvir: application to dosage forms and human plasma Luminescence 35 (4), 486-492 (2020)
- 15 Mater H Mahnashi, Ashraf M Mahmoud, Saad A Alkahtani, Ramadan Ali and Mohamed M El-Wekil A novel imidazole derived colorimetric and fluorometric chemosensor for bifunctional detection of copper (II) and sulphide ions in environmental water samples Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 228 (2020) 117846
- 16 Saad A Alkahtani, Ashraf M Mahmoud,Mater H Mahnashi,Ramadan Ali andMohamed M El-Wekil, Facile fabrication of a novel 3D rose like lanthanum doped zirconia decorated reduced graphene oxide nanosheets: An efficient electro-catalyst for electrochemical reduction of futuristic anti-cancer drug salinomycin during pharmacokinetic study Biosensors and Bioelectronic,150, 2020, 111849 (IF= 103)
- 17 Mater H Mahnashi, Ashraf M Mahmoud, Saad A Alkahtani, Ramadan Ali and Mohamed M El-Wekil Facile fabrication of a novel disposable pencil graphite electrode for simultaneous determination of promising immunosuppressant drugs mycophenolatemofetil and tacrolimus in human biological fluids Analytical and bioanalytical Chemistry,2020,412, 355-364
- 18 Mohamed Abdel-Lateef, Ramadan Ali, Mahmoud Omar, Sayed Derayea Novel spectrofluorimetric approach for determination of ledipasvir through UV-irradiation: application to biological fluids, pharmacokinetic study and content uniformity test RSC Adv, 2019,9, 34256-34264
- 19 Sayed M Derayea Ahmed A Hamad, Ramadan Ali and Hassan Refat H Ali Investigating erythrosine B as a fluorimetric probe for the determination of benzimidazole drugs via facile complexation reaction Microchemical Journal149, 2019, 104024
- 20 Mohamed Abdel-Lateef, Mahmoud Omar, Ramadan Ali, Sayed Derayea Employ fourier transform infrared spectroscopy for determination of second-generation anti-HCV (sofosbuvir, daclatasvir) drugs: Application to uniformity of dosage units Vibrational Spectroscopy 102, 2019, 47-51
- 21 Mohamed MEl-Wekil, Khaled K Afify, Randa A Abdel Salam, Ghada MHadad and RamadanAli Facile synthesis of novel nanocomposite prepared from spinel copper ferrite and reduced graphene oxide in the presence of anti-fouling agent diethyl ammonium acid sulphate for ultrasensitive detection of rosuvastatin in human plasma Microchemical Journal147, 2019, 1133-1140
- 22 Mohamed Oraby, Ahmed Khorshed, Ramadan Ali and Mohamed M Elsutohy A clinical study for the evaluation of pharmacokinetic interaction between daclatasvir and fluoxetine Journal of Pharmaceutical and Biomedical Analysis, 171, 2019 104-110
- 23 Ramadan Ali, Refat H, Batakoushy HA, Derayea S and Mohamed Elsotuhy A reductant colorimetric method for the rapid detection of certain cephalosporins via the production of gold and silver nanoparticles Microchemical Journal 145, 2019, 864-871
- 24 Mohamed Abdel-Lateef, Mahmoud Omar, Ramadan Ali, Sayed Derayea Xanthene based spectroscopic probe for the analysis of HCV antiviral, daclatasvir dihydrochloride, through feasible complexation reaction Microchemical Journal 145, 2019, 672-675
- 25 Ramadan Ali and Mohamed Elsotuhy Specific, highly sensitive and simple spectrofluorimetric method for quantification of daclatasvir in HCV human plasma patients and in tablets dosage form Open Chem, 2019 17: 116–126
- 26 Mohamed A Abdel-Lateef, Mahmoud A Omar , Ramadan Ali a, Sayed M Derayea Micellar spectrofluorimetric protocol for the innovative determination of HCV antiviral (daclatasvir) with enhanced sensitivity Application to human plasma and stability study Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 206 (2019) 57–64
- 27 Sayed M Derayea Ahmed A Hamad, Dalia M Nagy and Deena A Nour-Eldeen , Hassan Refat H Ali and Ali R Improved spectrofluorimetric determination of mebendazole, abenzimidazole anthelmintic drug, through complex formation with lanthanum (III) Application to pharmaceutical preparations andhuman plasma Journal of Molecular Liquids 272 (2018) 337–343
- 28 Mohamed M El-Wekil, Ashraf M Mahmoud, Saad A Alkahtani, Adel A Marzouk and Ali R A novel molecularly imprinted sensing platform based on MWCNTs/AuNPs decorated 3D starfish like hollow nickel skeleton as a highly conductive nanocomposite for selective and ultrasensitive analysis of a novel pan-genotypic inhibitor velpatasvir in body fluids Journal of Molecular Liquids 271, 2018, 105-111
- 29 Mahmoud A Omar, Mohamed A Abdel‐Lateef, Ramadan Ali, Sayed M Derayea Study on fluorescence properties of HCV antiviral (velpatasvir) and its fluorimetric determination in presence of sofosbuvir Application to stability study and human plasma Luminescence (2018) (Accepted)
- 30 Ramadan Ali, Adel A Marzouk, Reda A Abdelhameid, Mahmoud A Omar Specific stability indicating spectrofluorimetric method for determination of ledipasvir in the presence of its confirmed degradation products application in human plasma Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 202 (2018) 50–57
- 31 M M El-wekil, H Ali, A Marzouk and R Ali Synthesis of Fe3O4 nanobeads functionalized 8-hydroxyquinoline sulfonic acid supported with ion imprinted biopolymer as a recognition site for Al3+ ions: estimation in human serum and water samples New J Chem, 2018,
- 32 Mohamed M El-Wekil, Adel A Marzouk and Ali R Enhanced dispersive solid phase extraction assisted by cloud point strategy prior to fluorometric determination of anti-hepatitis C drug velpatasvir in pharmaceutical tablets and body fluids RSC Adv, 2018, 8, 13292
- 33 Mohamed M El-Wekil, Ashraf M Mahmoud, Saad A Alkahtani, Adel A Marzouk and Ali R A Facile Synthesis of 3D NiFe2O4 Nanospheres Anchored on a Novel Ionic Liquid Modified Reduced Graphene Oxide for Electrochemical Sensing of Ledipasvir: Application to Human Pharmacokinetic Study, Biosensors and Bioelectronic,2018, 109, 164-170
- 34 Ahmed A Hamad, Ali R, Hassan Refat H Ali, Dalia M Nagy and Sayed M Derayea Facile complexation reactions for the selective spectrofluorimetric determination of albendazolein oral dosage forms and spiked human plasma RSC Adv, 2018, 8, 5373
- 35 Mohamed A El Hamd, Ramadan Ali, Adel A Marzouk and OHA Validated Ultraviolet-Spectrometric Method for Determination of Sofosbuvir in Tablets Formulation Journal of Applied Pharmaceutical Science 7, 114-119
- 36 Refat H, Ali R, Batakoushy HA, Derayea S Solid-State FTIR Spectroscopic Study of Two Binary Mixtures: Cefepime-Metronidazole and Cefoperazone-Sulbactam Journal of Spectroscopy, 2017
- 37 Hamd MAE,Ali R, Haridy A, Dereyea S Abdelmegeed O Application of Hantzsch Reaction as a New Method for Spectrofluorimetric Determination of Some Cephalosporins Journal of Applied Pharmaceutical Science 2017, 7, 147-155
- 38 Refat H, Ali R, Batakoushy HA, Derayea S Spectroscopic Analysis and Antibacterial Evaluation of Certain Third Generation Cephalosporins Through Metal Complexation Anal Chem Lett, 7:4, 445-457
- 39 Shaaban B, Ali R, Derayea S,Omar M Sensitive spectrofluorimetric protocol for the determination of fluoxetine and paroxetinethrough binary complex formation with eosin Y Anal Chem Lett 2016, 6, 508-517
- 40 Hamd MAE, Ali R, Abdellatif AAH Non-Aqueous Titrimetric Assay for Determination of Loratadine in Pharmaceutical Preparations J Anal Bioanal Tech 2016,7:294
- 41 Ahmed A H Abdellatif, Mohamed A El Hamd, Ali R and Khaled I Saleh FORMULATION AND EVALUATION OF ORAL SUSTAINED RELEASE ETHYL CELLULOSE MICROPARTICLES Bull Pharm Sci, Assiut University, Vol 39, 2016, pp 27-41
- 42 Campos B, Weisang S, Osswald F, Ali R, Sedlmeier G, Bageritz J, Mallm JP, Hartmann C, von Deimling A, Popanda O, Goidts V, Plass C, Unterberg A, Schmezer P, Burhenne J, Herold-Mende C Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma Glia 2015 63:1850-9
- 43 Zembruski NC, Nguyen CD, Theile D, Ali RM, Herzog M, Hofhaus G, Heintz U, Burhenne J, Haefeli WE, Weiss J Liposomal sphingomyelin influences the cellular lipid profile of human lymphoblastic leukemia cells without effect on P-glycoprotein activity Mol Pharm 2013 10:1020-34
- 44 Ali R, Campos B, Dyckhoff G, Haefeli WE, Herold-Mende C, Burhenne J Quantification of retinoid concentrations in human serum and brain tumor tissues Anal Chim Acta 2012725:57-66
- 45 Campos B, Centner F-S, Bermejo JL, Ali R, Dorsch K, Wan F, Felsberg J, Ahmadi R, Grabe N, Reifenberger G, Unterberg A, Burhenne J, Herold-Mende C Aberrant expression of retinoic acid signalling molecules influences patient survival in astrocytic gliomas Am J Pathol 2011178:1953-64
- 46 Ibrahim A Darwish, Alaa S Khedr, Hassan F Askal, Ramadan M Mahmoud Stability-Indicating Thin-Layer Chromatographic Method for Quantitative Determination of Ribavirin J Chromatogr Sci 46 (2008) 4-9
- 47 Hassan F Askal, Alaa S Khedr, Ibrahim A Darwish, Ramadan M Mahmoud Quantitative Thin-Layer Chromatographic Method for Determination of Amantadine Hydrochloride Intl J Biomed Sci 4 (2008) 155-160
- 48 Ibrahim A Darwish, Alaa S Khedr, Hassan F Askal, Ramadan M MahmoudApplication of Inorganic Oxidants to the Spectrophotometric Determination of Ribavirin in Bulk and Capsules J AOAC Intl 89 (2006) 341-351
- 49 Ibrahim A Darwish, Alaa S Khedr, Hassan F Askal, Ramadan M Mahmoud Simple and Sensitive Spectrophotometric Methods for Determination of Amantadine Hydrochloride J Appl Spectrosc 37 (2006) 706-711
- 50 Ibrahim A Darwish, Alaa S Khedr, Hassan F Askal, Ramadan M Mahmoud Use of Oxidation Reactions for the Spectrophotometric Determination of Acyclovir and Amantadine Hydrochloride in their Dosage Forms Anal Chem: Ind J 1 (2005)
- 51 Ibrahim A Darwish, Alaa S Khedr, Hassan F Askal, Ramadan M Mahmoud Simple Fluorimetric Method for Determination of Certain Antiviral Drugs via their Oxidation with Cerium (IV) IL Farmaco 60 (2005) 555-562
- Ramadan Ali and Mohamed M El-Wekil A dual-recognition-controlled electrochemical biosensor for selective and ultrasensitive detection of acrylamide in heat-treated carbohydrate-rich food Food Chemistry Volume 413, 1 July (2023), 135666
- Ramadan Ali , Mohamed M El-Wekil Construction of MIP/Bi2S3 nanoparticles/rGO nanoprobe for simultaneous electrochemical determination of amoxicillin and clavulanic acid Journal of Alloys and Compounds, 962 (2023)1711800
- Yahya S Alqahtani Ashraf M Mahmoud, Mater H Mahnashi, Ramadan Ali, Reem Y Shahin, Mohamed M El-Wekil and Hany A Batakoushy Facile fabrication of boron and nitrogen co-doped carbon dots for “ON–OFF–ON fluorescence sensing of Al3+ and F− ions in water samples RSC Adv, 2023, 13, 23736
- Khaled K Afify, Ramadan Ali, Mohammad A El-Dosoky and Mohamed wafaa I Nassar3 HPLC/UV approach method for the first simultaneous estimation of molnupiravir and ertapenem as a binary mixture in human plasma and dosage form as a regimen for COVID-19 treatments BMC Chemistry (2023) 17:121
- 4 Ali O AlQarni, Ashraf M Mahmoud, Ramadan Ali and Mohamed M El-Wekil Colorimetric and fluorometric dual-mode determination of hypochlorite based on redox-mediated quenching RSC Adv, (2023), 13, 32492-32501
- https://scholargooglecomeg/citations?user=Af6r2EcAAAAJ&hl=ar
| اسم المشروع | وصف المشروع |
|---|---|
| لا يوجد | لا يوجد |
| Fluorescence-Based Detection of Perphenazine Using Biowaste-Derived Carbon Dots: A Pharmacokinetic Study | مسار تمويل أبحاث الطلبة / Student Research Funding Track |
| Sensing the invisible: Ultrasensitive and selective colorimetric detection of E coli O157:H7 based on masking the peroxidase-mimetic activity of aptamer-modified Au/Fe3O4 | Escherichia coli O157:H7 (E coli O157:H7) emerges as a significantly worrisome pathogen associated with foodborne illnesses, emphasizing the imperative for creating precise detection tools In this investigation, we developed a sensitive colorimetric biosensor for detecting E coli O157:H7 It was constructed using a nanozyme comprised of Au@Fe3O4 NPs, which was fabricated and subsequently modified with an aptamer (Apt) The nanozyme harnesses its inherent peroxidase-like activity to facilitate the transformation of reduced TMB into its oxidized form in the presence of H2O2, resulting in a noticeable shift to a blue color However, the presence of E coli O157:H7 effectively diminished the absorbance of oxidized TMB Consequently, the normalized absorbance at 652 nm demonstrates a linear decrease corresponding to concentrations of E coli O157:H7 within the range of 101 to 108 CFU mL−1 with a low limit of detection (LOD, S/N = 3) of 3 CFU mL−1 |
| Fluorometric detection of quinolones via AIE and FRET with terbium-doped carbon dots and copper nanoclusters | Terbium and nitrogen co-doped carbon dots (Tb@N-CDs), combined with α-lipoic acid-functionalized copper nanoclusters (LA@CuNCs), were proposed for the ratiometric detection of quinolone (QA) antibiotics In this system, Tb@N-CDs facilitate the aggregation of LA@CuNCs, enhancing its fluorescence emission at 670 nm via aggregation-induced emission enhancement (AIEE) Meanwhile, the fluorescence emission of Tb@N-CDs at 460 nm diminishes due to Förster resonance energy transfer (FRET) Upon the introduction of QA, the binding between Tb3+ ions and N-CDs weakens, disrupting both AIEE and FRET processes This disruption results in a reduction in fluorescence emission at 670 nm and a concurrent increase at 460 nm The fluorescence response ratio (F460/F670) increases with higher concentrations of ciprofloxacin (CFX), demonstrating a linear range from 0008 to 120 μmol L−1 and LOD of 16 nmol L−1 The method successfully detected CFX in milk and urine samples, achieving recoveries between 977 % and 1038 %, RSD of less than 379 % |
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