JAMSHEED JAVID SYED ASGAR ALI
Experience and administrative positions
- ASSISTANT PROFESSOR (2015 - Present)
- CHAIRMAN, Statistics and Information Unit, FAMS, UT (2018- till date)
- MEMBER & STATISTICAL ANALYST, Quality and Academic Accreditation Committee, FAMS, UT (2017- till date)
- MEMBER, Continuous Education and E-Learning Committee (2020- till date)
- MEMBER, Scientific research Committee, Prince Fahd Bin Sultan Research Chair, FAMS, UT (2015- till date)
Qualifications
- PhD Medical Biochemistry
Research interests
Non-Invasive Molecular diagnostic Markers
Molecular mechanisms of drug target & drug resistance
Novel Molecular mechanisms
- Evaluation of the Association of Omentin 1 rs2274907 A T and rs2274908 G A Gene Polymorphisms with Coronary Artery Disease in Indian Population: A Case-Control Study J Pers Med 2020 Oct 2610(4):194 doi: 103390/jpm10040194PMID: 33114503 (Pubmed Indexed)
- Molecular Evaluation of MicroRNA-146 Gene Variability (rs2910164 C G) and its Association with Increased Susceptibility to Coronary Artery DiseaseMicrorna 2020 Dec 9 doi: 102174/2211536609666201209151130 Online ahead of printPMID: 33297927 (Pubmed Indexed)
- The Promising Signatures of Circulating microRNA-145 in Epithelial Ovarian Cancer Patients Microrna 20209(1):49-57 doi: 102174/2211536608666190225111234PMID: 30799804 (Pubmed Indexed)
- Incidence of MicroR-4513C/T Gene Variability in Coronary Artery Disease - A Case-Control Study Endocr Metab Immune Disord Drug Targets 201919(8):1216-1223 doi: 102174/1871530319666190417111940PMID: 31038082 (Pubmed Indexed)
- Potential Impact of MicroRNA-423 Gene Variability in Coronary Artery Disease Endocr Metab Immune Disord Drug Targets 201919(1):67-74 doi: 102174/1871530318666181005095724PMID: 30289085 (Pubmed Indexed)
- MicroRNA-224 (rs188519172 AG) Gene Variability is Associated with a Decreased Susceptibility to Coronary Artery Disease: A Case-Control Study Microrna 20198(3):198-205 doi: 102174/2211536608666181211153859PMID: 30539710 (Pubmed Indexed)
- Potential Impact of COMT-rs4680 G A Gene Polymorphism in Coronary Artery Disease J Cardiovasc Dev Dis 2018 Jul 135(3)(Pubmed Indexed)
- Clinical significance of circulatory miRNA-21 as an efficient noninvasive biomarker for the screening of Lung cancer patients Asian Pac J Cancer Prev 2018 Sep 2619(9):2607-2611(Pubmed Indexed)
- A Germline Mutation in the BRCA1 3’UTR Variant Predicts Susceptibility to Breast Cancer in a Saudi Arabian Population Asian Pac J Cancer Prev 2018 Mar 2719(3):859-866(Pubmed Indexed)
- A deletion polymorphism in the RIZ gene is associated with increased progression of imatinib treated chronic myeloid leukemia patients Leuk Lymphoma 2017 Jul58(7):1694-1701 (Pubmed Indexed)
- Utility of amplification Refractory Mutation System PCR for the detection of JAK2 mutation in Chronic Myeloproliferative Disorders Int J Adv Res2017 5(1): 829-837
- Optimization of allele specific PCR (AS-PCR) for the early detection of FLT3 (D835Y) mutation in Acute Myeloid Leukemia patients at Tabuk, Saudi Arabia Int J Adv Res Jan 2017 5(1), 817-822
- Involvement of CASP3 promoter polymorphism (-1337 C G) in the development and progression of non-small cell lung cancer Tumour Biol 2016 Jul37(7):9255-62 (Pubmed Indexed)
- Detection of HER2 polymorphism and expression using circulating DNA and RNA as a tool in lung adenocarcinoma patients: a case control study Ann Transl Med 2016 Jun4(11):209 (Pubmed Indexed)
- Clinical implications of cytosine deletion of exon 5 of P53 gene in non small cell lung cancer patients South Asian J Cancer 2016 Jan-Mar5(1):33-6(Pubmed Indexed)
- The C609T (Pro187Ser) Null Polymorphism of the NQO1 Gene Contributes Significantly to Breast Cancer Susceptibility in North Indian Populations: a Case Control Study Asian Pac J Cancer Prev 201617(3):1215-9(Pubmed Indexed)
- Clinical significance of TP53 (R72P) and MDM2 (T309G) polymorphisms in breast cancer patients Clin Transl Oncol 2016 Jul18(7):728-34 (Pubmed Indexed)
- Prognostic significance of serum ERBB3 and ERBB4 mRNA in lung adenocarcinoma patients Tumour Biol 2016 Jan37(1):857-63 (Pubmed Indexed)
- Glutathione S-transferase M1 and T1 (rs4025935 and rs71748309) null genotypes are associated with increased susceptibility to coronary artery disease in Indian populations Acta Cardiol 201671(6):678-684 (Pubmed Indexed)
- Role of survivin re-expression in the development and progression of non-small cell lung cancerTumour Biol 2015 Jul36(7):5543-50 (Pubmed Indexed)
- Association of p53 and mdm2 in the development and progression of non-small cell lung cancer Tumour Biol 2015 Jul36(7):5425-32 (Pubmed Indexed)
- Extracellular cytochrome c as a biomarker for monitoring therapeutic efficacy and prognosis of non-small cell lung cancer patients Tumour Biol 2015 Jun 36(6):4253-60(Pubmed Indexed)
- CC genotype of anti-apoptotic gene BCL-2 (-938 C/A) is an independent prognostic marker of unfavorable clinical outcome in patients with non-small-cell lung cancer Clin Transl Oncol 2015 Apr17(4):289-95 (Pubmed Indexed)
- BAX G(-248)A gene polymorphism and its association with risk of Non-small cell lung cancer- a case control study Open J Apoptosis, 2015 4(2):47-58
- Simple multiplex RT-PCR for identifying common fusion BCR-ABL transcript types and evaluation of molecular response of the a2b2 and a2b3 transcripts to Imatinib resistance in north Indian chronic myeloid leukemia patients Indian J Cancer 2015 Jul-Sep 52(3):314-8 (Pubmed Indexed)
- Clinical Significance of the NQO1 C609T Polymorphism in Non Small Cell Lung Adenocarcinoma Patients Asian Pac J Cancer Prev 201516(17):7653-8(Pubmed Indexed)
- Clinical Implication of EGF A61G Polymorphism in the Risk of Non Small Cell Lung Adenocarcinoma Patients: A Case Control Study Asian Pac J Cancer Prev 201516 (17):7529-34 (Pubmed Indexed)
- Cell Free EGFR mRNA Expression and Implications for Survival and Metastasis in Non-Small Cell Lung Cancer Cases Asian Pac J Cancer Prev 201516(15):6445-9 (Pubmed Indexed)
- Expression of serum miR-200a, miR-200b, and miR-200c as candidate biomarkers in epithelial ovarian cancer and their association with clinicopathological features Clin Transl Oncol 2015 Oct 17(10):779-87 (Pubmed Indexed)
- Polymorphism T81C in H-RAS Oncogene Is Associated With Disease Progression in Imatinib (TKI) Treated Chronic Myeloid Leukemia Patients World J Oncol 2015 Apr6(2):321-328 (Pubmed Indexed)
- RASSF1 & PTEN promoter hypermethylation influences the outcome in epithelial ovarian Cancer Clinical Ovarian and Other Gynecologic Cancer2015 DOI: 101016/ jcogc 2014 12002
- TP53 is a Mutational Target in Non Small Cell Lung Cancer Patients and its Pro/Pro Variant is Potentially Contributing to Cancer Susceptibility J Carcinogenesis & Mutagenesis 2013 4(1):1-7
- Biological and Clinical Implications of Functional Promoter Polymorphism of CASPASE 9 Gene in NSCLC Patients J Mol Biomarkers Diagn 2013 S (8):1-7
- TP53 Gene Polymorphism in Epithelial Ovarian Carcinoma Patients from North Indian Population and its Pro/Pro Variant is Potentially Contributing to Cancer Susceptibility J Genet Syndr Gene Ther 2013 4(5):1-6
- Epigenetic Silencing of DAPK1 Gene is Associated with Faster Disease Progression in Indian Populations with Chronic Myeloid Leukemia J Cancer Sci Ther 2013 5(4):144-149
- Inactivation of RIZ1 gene by promoter hypermethylation is associated with disease progression and resistance to Imatinib in Indian Chronic myelogenous leukemia patients, first study from India J Cancer Sci Ther 2013 5(2):045-051
- Inactivation of P16 (INK4a) Gene by Promoter Hypermethylation is Associated with Disease Progression in Chronic Myelogenous Leukaemia J Carcinogenesis & Mutagenesis 2013 4(2):1-6
- Biological and Clinical Implications of Exon 8 P53 (R282W) Gene Mutation in Relation to Development and Progression of Chronic Myeloid Leukaemia Patients in Indian Population J Cell Sci Ther 2013 4(1):1-6
- Clinical and Prognostic Significance of R282W p53 gene mutation in North India Patients with Non Small Cell Lung Carcinoma Translational Medicine 2012 2(2):1-5
- Impact of MDM2 SNP309TG Polymorphism: Increased risk of developing Non Small Cell Lung Cancer and Poor Prognosis in Indian Patients J Cancer Sci Ther20124(10):341-346
- Clinical and Prognostic Significance of Promoter Polymorphism (-31GC) of Anti Apoptotic Gene Survivin (BIRC5) in North Indian Patients with Non-Small Cell Lung Cancer J Cancer Sci Ther2012 4(9):276-280
| Project Name | Project Description |
|---|---|
| To investigate the role of circulatory miRNAs (c-miRNAs) as potential biomarkers for the early diagnosis of Lung Cancer | To develop PCR based genetic tests for the management of treatment among the patients with cardiovascular disease from Tabuk, Saudi Arabia |
| Molecular mechanisms responsible for acquired resistance to EGFR-tyrosine kinase inhibitors in Nonsmall cell lung cancer | Prognostic significance of apoptosis gene alterations in Non-small cell lung cancer patients |
- Best Young Scientist Award by Society of Cancer Research, India (2015)
- Senior Research Fellow, Department of Non Communicable Disease, Indian Council of Medical Research, New Delhi, India (2010-2014)
- DBT, BCIL Fellow, Department of Biotechnology: Ministry of Science and Technology New Delhi, India (2008-2009)
