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يعد معمل الكيمياء العضوية في قسم الكيمياء من المعامل البحثية الأولي التي انشئت في كلية العلوم بجامعة تبوك، حيث تم تأسيسه عام 1435 هـ من أجل توفير مركبات عضوية جديدة آمنة تستخدم لبعض الحالات المرضية وخاصة الأورام السرطانية مثل سرطان الثدي والبروستاتا والقولون والتي تحدث بسبب انتشار المواد الكيماوية المسرطنة وبعض الأمراض الفيروسية مثل التهاب الكبد الفيروسي والإشعاع الذري والنووي والتدخين.
Mahmoud A. Abdelaziz Mahmoud, Rafat M. Mohareband Meshari. A. Al-Sharif Heterocyclization of Thiophenes Derived from Estrone Followed by Cytotoxic, HTRF Kinase and Pim Kinase Evaluations. Anti-Cancer Agents in Medicinal Chemistry, 2018, 18, 1711-1728
Rafat M. Mohareb, Fatima Al-Omran, Mahmoud A. Abdelaziz and Rehab A. Ibrahim, 4Anti-inflammatory and Anti-ulcer Activities of New Fused Thiazole Derivatives Derived from(2-Oxo-2H-chromen-3-yl)thiazol-4(5H)-one. Acta Chim. Slov. 2017, 64, 349–364
Mahmoud A. Abdelaziz Mahmoud, Synthesis and Bioactivity Evaluation of New Heteroaromatic Substituted Pteridines as Anticancer Agents. Jokul Journal Vol 66, No. 2;Feb 2016
Nahed N.E. El-Sayed , Mahmoud A. Abdelaziz, Wagnat W. Wardakhan , Rafat M. Mohareb , The Knoevenagel reaction of cyanoacetylhydrazine with pregnenolone: Synthesis of thiophene, thieno[2,3-d]pyrimidine, 1,2,4-triazole, pyran and pyridine derivatives with anti-inflammatory and anti-ulcer activities. Steroids. 2016 Mar;107:98-111.
Mahmoud A. Abdelaziz Mahmoud, Design and synthesis of new thiophene derivatives together with their antitumor evaluations. European Journal of Chemistry 6 (4) (2015) 444?450
Mahmoud A. Abdelaziz, Hend M. El- Sehrawi & Rafat M. Mohareb Synthesis, cytotoxicity and toxicity of thieno[2,3-d]pyrimidine derivatives derived from 2-amino-3-cyano-4,5,6,7- tetrahydrobenzo[b]thiophene. Med Chem Res (2015) 24:3932–3948
Mohamed Sobhi Motawea and Mahmoud Ali Abdelaziz. Some pyrazole derivatives as corrosion inhibitors for carbon steel in hydrochloric acid solutions European Journal of Chemistry 6 (3) (2015) 342?349
Rafat M. Mohareb , Nermeen S. Abbas , Mahmoud A. Abdelaziz . Heterocyclic ring extension of androstenedione: Synthesis and cytotoxicity of fused pyran pyrimidine and thiazole derivatives. Steroids 86 (2014) 45–55
Rafat M. Mohareb , Amira E. M. Abdallah , Mahmoud A. Abdelaziz. New approaches for the synthesis of pyrazole, thiophene, thieno[2,3-b]pyridine, and thiazole derivatives together with their anti-tumor evaluations. Med Chem Res (2014) 23:564–579
10. Danish Khan, Naseem Ahmed, Meshari A. Alsharif, Mohammed Issa Alahmdi, and Sayeed Mukhtar, "SeO2 Mediated Synthesis of Selected Heterocycles by Oxidative C-C Bond Cleavage of AcetophenoneDerivatives" ChemistrySelect, 2019, 4,7585–7590. (impact factor 1.716, ISI Journal) DOI: 10.1002/slct.20190121
11. Mohd Waheed, Naseem Ahmed, Meshari A.Alsharif, Mohammed Issa Alahmdi, and Sayeed Mukhtar, " K2S2O8-Mediated Efficient Oxidative Deoximation of Flavonoid Oximes under Mild Reaction Conditions" ChemistrySelect, 2019, 4,7572–7576(impact factor 1.716, ISI Journal) DOI: 10.1002/slct.201901554
12. Mohd Waheed, Naseem Ahmed, Meshari A Alsharif, Mohammed Issa Alahmdi, and Sayeed Mukhtar, “PhI(OAc)2-Mediated One-Pot Synthesis and their Antibacterial Activity of Flavone and Coumarin Based Isoxazoles Under Mild Reaction Conditions”Chemistry Select;4 (2019) 1872–1878. (impact factor 1.716, Science Citation Index Expanded)
13. Meshari A. Alsharif, Danish Khan, Sayeed Mukhtar, Mohammed Issa Alahmdi, and Naseem Ahmed, KOtBu-Mediated Aza-Michael Addition of Aromatic Amines or N-Phenylurea to 3-Nitro-2-phenyl-2H-chromenes and Sequential Aerobic Dehydrogenation, Eur. J. Org. Chem. 2018(26)(2018) 3434-3463.(Impact factor: 3.029, ISI Journal)
14. Meshari A. Alsharif, Sayeed Mukhtar, Abdullah M. Asiri, Salman A. Khan,“One pot synthesis, physicochemical and photophysical investigation of biologically active pyridine-3-carboxylate (ECPC) as probe to determine CMC of surfactants inorganized media”, Colloids and Surfaces A, 543 (2018) 38-45. (impact factor: 3.131, ISI journal)
15. Mohd Waheed, Naseem Ahmed, Meshari A Alsharif, Mohammed Issa Alahmdi and Sayeed Mukhtar “One-Pot Synthesis of 1,5-Diketones from 3-acetyl-4- Hydroxycoumarin and Effective Cyclization to Unexpected 3, 4-Dihydropyridines’ Org. Biomol. Chem., 16 (2018) 3428. (impact factor: 3.564, ISI journal)
16. Sayeed Mukhtar, Meshari A. Alsharif, Mohammed I. Alahmdi , Humaira Parveen, “Synthesis, Characterization, Stereochemistry and Biological Evaluation ofNovel Cyclohexanol Derivatives”, Asian Journal of Chemistry, vol. 30, No. 5 (2018) 1102-1108. (RG impact factor 0.19, Listed in scopus)
17. Humaira Parveen, Raedah Aiyed Suliman Alatawi, Meshari A. Alsharif, Mohammed Issa Alahmdi, Sayeed Mukhtar, Salman Ahmad Khan, Sadaf Hasan, Asad U. Khan, “Novel Pyrazoline-based Organometallic Compounds Containing Ferrocenyl and Quinoline units: Synthesis, Characterization and Microbial susceptibilities”. Appl. Organomet. Chem., 32(4) (2018) e4257. (Impact factor: 3.581, ISI Journal)
18. Mohammed Waheed, Naseem Ahmed, Meshari A. Alsharif, Mohammed Issa Alahmdi and Sayeed Mukhtar; “An Efficient Synthesis of2,4,5-Trisubstituted and 1,2,4,5-Tetrasubstituted Imidazoles Using Dihydroquinolines as Novel Organocatalyst”, Chemistry Select;2(26) (2017 )7946–7950. (impact factor 1.716, Science Citation Index Expanded)
19. Danish Khan, Sayeed Mukhtar, Meshari A. Alsharif, Mohammed Issa Alahmdi, Naseem Ahmed, “PhI(OAc)2 mediated an efficient Knoevenagel reaction and their synthetic application for coumarin derivatives”, Tetrahedron Lett. , 58 (2017) 3183–3187. (Impact factor 2.379, ISI Journal)
20. Humaira Parveen, Meshari A. Alsharif, M.I. Alahmdi, S. Mukhtar, A. Azam, “Novel pyrimidine-based ferrocenyl substituted organometallic compounds: Synthesis, characterization and Biological evaluation”. Applied Organometalic Chemistry, Appl. Organomet. Chem., 32(4) (2018) e4261. (Impact factor: 3.581, ISI Journal)
21. Humaira Parveen, Raedah Aiyed Suliman Alatawi, Nadia Hussein El Sayed, Sadaf Hasan, Sayeed Mukhtar, Asad U. Khan, “Synthesis, characterization and biological evaluation of some novel nitrogen and sulphur containing organometallic heterocycles”,Arabian Journal of Chemistry, vol. 10 (8) (2017) 1098-1106. (impact factor: 2.969 ISI journal)
22. Sayeed Mukhtar, Mohammed Issa Al-Ahmdi and Humaira Parveen, Synthesis, Stereochemistry and Antimicrobial activity of some Novel Flavanone-hydrazono-thiazolidin-4-ones from Flavanones”, Asian Journal of Chemistry; Vol. 28, No. 12, (2016), 2589-2595. (RG impact factor 0.19, Listed in scopus)
23. Humaira Parveen, Sayeed Mukhtar, Amir Azam; Novel Ferrocenyl Linked Pyrazoline Analogs as Potent Anti-amoebic Agents, Journal of heterocyclic chemistry, vol. 53, (2), (2016), 473-478. (impact factor: 1.141, ISI journal)
24. Humaira Parveen, Raedah Aiyed Suliman Alatawi, Salman Ahmad Khan, Mohammed Issa Al-Ahmdi, Sayeed Mukhtar, Amir Azam and Nadia Hussein El Sayed, Synthesis, Characterization and Biological Evaluation of Novel 1-N-Substituted Thiocarbomoyl-3-Ferrocenyl-2- Pyrazoline Derivatives”, Asian Journal of Chemistry; Vol. 28, No. 8 (2016), 1835-1840. (RG impact factor 0.19, Listed in scopus)
25. Sayeed Mukhtar, Waleed Atef Manasra ,Humaira Parveen ,Amir Azam, Synthesis Characterization, Antiamoebic activity and Toxicity of Ferrocenyl Chalcones, Asian Journal of Chemistry. Vol. 26, No. 24 (2014), 8407-8412. (RG impact factor 0.19, Listed in scopus)
26. Humaira Parveen, Sayeed Mukhtar, Nadia Hussein El Sayed, Faisal Hayat, Synthesis, characterization and antimicrobial activity of long chain fatty alkenoates of metronidazole and their novel tetrazole derivatives, Asian Journal of Chemistry. Vol. 26, No. 23 (2014), 8134-8138. (RG impact factor 0.19, Listed in scopus)
27. Humaira Parveen, Faisal Hayat, Sayeed Mukhtar, Attar Salahuddin, Andleeb Khan, FakhrulIslam, Amir Azam, Synthesis, characterization and biological evaluation of novel 2,4,6-trisubstituted bis-pyrimidine derivatives, European Journal of Medicinal Chemistry, 46, 2011, 4669-4675. (impact factor: 4.186, ISI journal).