الصفحة الرئيسية

كلية الطب \ الطب والجراحة

محمد أحمد حسن عثمان مسيك

السيرة الذاتية
نسبة اكتمال الملف الشخصي
الجنسية السودانية
التخصص العام الأحياء الدقيقة
التخصص الدقيق تقنية حيوية
المسمى الوظيفي أستاذ مساعد
الدرجة العلمية (المرتبة) دكتوراه

نبذه مختصرة

Prof Mesaik Is a professor of Microbiology and Immunology with a vast experience on Research related to Biological activities of immunomodulators with a research experience since 2003 quidding MPhil and PhD student and leading a research teams

المؤهلات العلمية

2003, Ph D (Microbiology) Thesis Title “Studies on Some Natural Compounds for their Immunomodulatory Activity Department of Microbiology and HEJ Research Institute of Chemistry, University of Karachi, Pakistan 1996, M Phil (Biotechnology) Thesis Title “PCR Based Diagnosis and Genotyping of Hepatitis C Virus, In-Patient with Chronic Liver Disease, from Faisalabad Region Department of Biological Sciences, Quaid-I-Azam University, Islamabad, Pakistan and National Institute for Biotechnology & Genetic Engineering Faisalabad Pakistan 1994, M Sc (Clinical Microbiology) and 1993, B Sc Hons (Micro, Bio & Physiology) Shah Abdul Latif University, Khairpur, Pakistan

الاهتمامات البحثية

inflammation, Immunology cytokine inhibition Medical Microbiology Molecular Immunology Natural Cytokine Inhibitors Natural products Immunomodulatory and biological activity

الخبرات والمناصب الإدارية

Professor of Microbiology and Immunology (October 2020)Faculty of Medicine University of TabuK Associate Professor (Microbiology & Immunology) (March 2016 - 2020) Associate Professor (Microbiology & Immunology) (March 2016- 2020) Faculty of Medicine University of Tabuk, Tabuk 71491 Saudi Arabia PO Box 741 and Medical Microbiology Deptt Head, Faculty of Medicine University of Tabuk (October 2016-October 2017) 2020 Associate Professor (Microbiology & Immunology) (January 2014- March 2016) Faculty of Pharmacy National University of Malaysia, (UKM) KL Malaysia Assistant Professor (March 2007- Jan 2014) Dr Panjwani Center for Molecular Medicinal & Drug Research PCMD, International Center for Chemical Sciences ICCBS), University of Karachi, Karachi 75270 Pakistan & serve as Head of Molecular Immunology Lab as well In-charge of cell culture facility at Dr panjwani center for Molecular Medicine and Drug Research (2005-2013) Senior Research Associate (Jan 2004 –March 2007) PCMD, ICCBS, University of Karachi, Karachi 75270 Pakistan Research Fellow (PhD Program) (May, 1997 - Oct 2003) Microbiology Department University of Karachi & HEJ Research Institute of Chemistry, International Center for Chemical Sciences, University of Karachi, Karachi-75270, Pakistan Junior Research fellow (MPhil Program) (August 1994 - November 1996)

الجدول الدراسي
الأبحاث والمؤلفات
  • 1 Faizi S, Sarfaraz T, Sumbul S, Jabeen A, Halim SA, Mesaik MA, Ul-Haq Z Synthesis of Novel 8-Hydroxyquinoline Derivatives through Mannich Reaction and their Biological Evaluation as Potential Immunomodulatory Agents (2019) Med Chem 202016(4):531-543
  • 2 Samreen Soomro, M Ahmed Mesaik, Rafat Siddique, Noureen Khan, Sobia Ahsan Halim, Zaheer Ul-Haq, F Shaheen and M Iqbal Choudhary Inhibitory effects of Myrtocumaoacetalone 1 from Myrtus communis on infammatory response in mouse macrophages (2019) Molecules 2019 Dec 1825(1):13
  • 3 Muhammad S Ali, Ghafoor Ahmed, M Ahmed Mesaik, Muhammad R Shah, M Lateef and Muhammad I Ali Facile one pot syntheses of new C-28 esters of oleanolic acid and studies on their antiproliferative effect on T-cells (2018) Z Naturforsch C 2018 Nov 2773(11-12):417-421 doi: 101515/znc-2018-0028
  • 4 Javaid Alam, Ibrahim Jantan, Mohd Azlan Nafiah, Endang Kumolosasi, Muhammed Ahmed Mesaik Suppressive Effects of the Standardized Extract of Phyllanthus amarus on Type II collagen-induced Rheumatoid Arthritis in Sprague Dawley Rats (2018) Current pharmaceutical biotechnology DOI: https://doiorg/102174/1389201020666181211124954
  • 5 Abeysekera WKSM, SPG Arachchige, M Ahmed Mesaik, M Iqbal Choudhary, WD Ratnasooriya, N V Chandrasekharan, Almas Jabeen, Samreen Soomro Crude Bran Extracts and Fractions of Selected Traditional Red Rice (Oryza sativa L) Varieties of Sri Lanka Potentiates Anti-Inflammatory Activities in Human Blood and Cell Assays (2018) Adv Biochem Biotehcnol: ABIO-161 DOI: 1029011/2574-7258 000061
  • 6 Ahmed M Mesaik, , Hiap Wei Poh, , Ooi Yan Bin, , Izzaddinn Elawad, Badr Alsayedn IVivo Anti-Inflammatory Anti-Bacterial and Anti-Diarrhoeal Activity of Ziziphus Jujuba Fruit Extract Open Access Maced J Med Sci (2018) 156(5):757-766 https://doiorg/101080/1049647520181463931
  • 7 Fouzia Khan, Nida Dastagir, Mehreen Lateef, Muhammad Yousuf, Zulfiqar Ali Mirani, Ahmed Mesaik, Shaheen Faizi & Shahana Urooj Kazmi Immunomodulatory activities of extracts of Caesalpinia pulcherrima Journal of Herbs, Spices & Medicinal Plants 24 (3) (2018) https://doiorg/101080/1049647520181463931
  • 8 Oladimeji AO, Oladosu IA, Jabeen A, Faheem A, Mesaik MA, Ali MS Immunomodulatory activities of isolated compounds from the root-bark of Cussonia arborea Pharm Biol (2017) 55(1):2240-2247
  • 9 Erukainure OL, Mesaik MA, Atolani O, Muhammad A, Chukwuma CI, Islam MS Pectolinarigenin from the leaves of Clerodendrum volubile shows potent immunomodulatory activity by inhibiting T - cell proliferation and modulating respiratory oxidative burst in phagocytes Biomed Pharmacother (2017) 93:529-535
  • 10 Ochuko L Erukainure, Moses Z Zaruw, Ahmed M Mesaik, Aliyu Muhammad, Jeffery O Adoga, Ibukun O Ogunyemi, Osaretin AT Ebuehi and Gloria N Elemo Suppression of phagocytic oxidative burst, cytotoxic effect, and computational prediction of oral toxicity of dietary fatty acids of Clerodendrum volubile stem Comp Clin Pathol (2017) doi:101007
  • 11 Erukainure OL, Hafizur RM, Choudhary MI, Adhikari A, Mesaik AM, Atolani O, Banerjee P, Preissner R, Muhammad A, Islam MS Anti-diabetic effect of the ethyl acetate fraction of Clerodendrum volubile: protocatechuic acid suppresses phagocytic oxidative burst and modulates inflammatory cytokines Biomed Pharmacother (2017) 86: 307-315
  • 12 Ul-Haq Z, Naz S, Mesaik MA Interleukin-4 receptor signaling and its binding mechanism: A therapeutic insight from inhibitors tool box (2016) Cytokine Growth Factor Rev 32:3-15
  • 13 Ilangkovan M, Jantan I, Mesaik MA, Bukhari SN Inhibitory Effects of the Standardized Extract of Phyllanthus amarus on Cellular and Humoral Immune Responses in Balb/C Mice (2016) Phytother Res 30(8): 1330-8
  • 14 Erukainure OL, Mesaik AM, Muhammad A, Chukwuma CI, Manhas N, Singh P, Aremu OS, Islam MS Flowers of Clerodendrum volubile exacerbate immunomodulation by suppressing phagocytic oxidative burst and modulation of COX-2 activity (2016) Biomed Pharmacother 83:1478-1484
  • 15 M Iqbal Choudhary Saira Bano Atia-tul Wahab Sammer Yousuf Almas Jabeen M Ahmed Mesaik Atta-ur- Rahman New Anti-inflammatory Metabolites by Microbial Transformation of Medrysone (2016) PLOS ONE 2211(4)
  • 16 Almas Jabeen, M Ahmed Mesaik, Shabana Simjee, Samina Bano and Shaheen Faizi Anti TNF-α and anti-arthritic effect of patuletin: a rare flavonoid from Tagetes patula (2016) Inter Immunophamcol 36: 232-40
  • 17 OL Erukainure, OAT Ebuehi, MI Choudhary, MA Mesaik, A Shukralla, Orange Peel Extracts: Chemical Characterization, Antioxidant, Antioxidative Burst, and Phytotoxic Activities (2016) Journal of dietary supplements 13 (5), 585-594
  • 18 IE Orhan, MA Mesaik, A Jabeen, Y Kan Immunomodulatory properties of various natural compounds and essential oils through modulation of human cellular immune response (2016) Industrial Crops and Products 81, 117-122
  • 19 Khan KM, Mesaik MA, Abdalla OM, Rahim F, Soomro S, Halim SA, Mustafa G, Ambreen N, Khalid AS, Taha M, Perveen S, Alam MT, Hameed A, Ul-Haq Z, Ullah H, Rehman ZU, Siddiqui RA, Voelter W The immunomodulation potential of the synthetic derivatives of benzothiazoles: Implications in immune system disorders through in vitro and in silico studies (2016) Bioorg Chem 64:21-8
  • 20 N Iqbal, A Adhikari, N Kanwal, OM Abdalla, MA Mesaik, SG Musharraf New immunomodulatory steroidal alkaloids from Sarcococa saligna (2015) Phytochemistry Letters 14, 203-208
جوائز التميز
  • Awarded a Certificate of Distinguish Researcher by the Dean Faculty of Medicine for 2019 and 2020
المشاريع البحثية
اسم المشروع وصف المشروع
2 Effects of Hibiscus Sabdariffa on high blood pressure and lipid profile among adult hypertensive patients Funded by Faculty of Scientific Research, University of Tabuk (1439-1440)
1 In silico, toxicological and analytical studies on the constituents of the smokeless tobacco (Shammah) Funded by Faculty of Scientific Research, University of Tabuk (1439-1440)
3 Antidiarrheal And Antibacterial Activities Of Aqueous And Ethanol Extract Of Ziziphus Jujuba Fruit In Mice Funded by Faculty of Scientific Research, University of Tabuk (1437-1438)
4 Studies on the anti-inflammatory protective effect of phyllanthus niruri extract and its biomarker compounds on human monocytic cell lines and adjuvant induced arthritis rat model Funded by Herbal Development Office Ministry of Agriculture and Agro-based Industry, Malaysia, (NKEA Research Grant Scheme-NRGS NF 2015-005) (PhD student research project) (2014-2016)
5 Studies and Immunomodulatory activities of some Malaysian Medcinal Plants, (PhD Student Research Project at Faculty of pharmacy UKM, KL Malaysia) (Ministry of Science, Technology and Innovation, Malaysia Grant No 02-01-02-SF0932) (2014-2018)
6 Studies on Honey Proteins and Peptides and Their Role in Modulation of Innate/Adaptive Immune System M Phil/Ph D Research Project in Molecular Medicine at PCMD, ICCBS, University of Karachi, Pakistan Funded by Higher Education commission (HEC) Pakistan (2014-2017)
7 Immunomodulatory effect of natural flavonoids, triterpenoids, alkaloidal compounds and understanding the molecular basis of their inhibition: strategy for control of rheumatoid arthritis Funded by Higher Education commission (HEC) Pakistan 2010-2013
“Discovery of Immunomodulatory Natural Products and Understanding The Molecular Basis of Their Activity" Funded by Higher Education commission (HEC) Pakistan (2007-2011)
معلومات التواصل
البريد الإلكتروني : mmesaik@UT.EDU.SA
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